See our new paper on a rare variant of the proprotein PC2- which has unusually few SNPs- present as a founder mutation in an Amish population.
Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population.
Winters A, Ramos-Molina B, Jarvela TS, Yerges-Armstrong L, Pollin TI, Lindberg I.
Diabetes Res Clin Pract. 2017 Sep;131:82-90. doi: 10.1016/j.diabres.2017.06.023. Epub 2017 Jul 3.