7B2 chaperone knockout in APP model mice results in reduced plaque burden. Jarvela TS, Womack T, Georgiou P, Gould TD, Eriksen JL, Lindberg I. Sci Rep. 2018 Jun 28;8(1):9813. doi: 10.1038/s41598-018-28031-7. PMID: 29955078
This paper shows that the loss of 7B2, like that of clusterin, has a paradoxical protective effect on brain amyloid deposition.